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Traditional healthcare has always waited for disease. Longevity doesn’t. Powered by the Empathy Engine®, for the first time, you can see aging itself, mapped across six dimensions and 24 drivers and support slowing it down before it impacts your health.
Diagnostics detect disease. Longevity helps you stay ahead.
101+ connects the dots between biomarkers, your data, and longevity research, illuminating the biological patterns that shape how you age and how your systems perform together, not apart. It looks beyond symptoms and single results to reveal the deeper connections guiding your HealthSpan.
Clinically validated. CLIA-certified. State-of-the-art.
The test is the world’s first longevity assessment powered by the Empathy Engine® to reveal your 6 core longevity dimensions and 24 drivers of aging. Each sample is processed in CLIA-certified laboratories to ensure medical-grade precision. Millions of data correlations then decode how your systems interact. This isn’t another lab test. It’s a breakthrough.
Your health isn’t defined by a single number. It’s shaped by key drivers of longevity spanning cellular repair, cardiovascular strength, metabolic balance, musculoskeletal resilience, stress and inflammation. The EmpathyEngine® decodes that story revealing where you can support and transform it.
It signifies your cell’s repair system for fixing DNA errors that prevent aging mutations.
It reflects how well your body balances oxidant damage with antioxidant defenses.
Reflects the accumulation of dead cells in your body that promote inflammation and accelerate aging.
It indicates the reserve of repair cells your body uses to regenerate tissues.
This reveals the hidden strain your heart carries before symptoms appear.
This highlights your body’s clot formation potential.
Indicates how strong & resilient your bones are against injury with age.
Shows your long-term ability to control glucose and insulin levels.
It signifies how well your kidneys filter waste to protect longevity.
Indicates your liver’s ability to detoxify, process nutrients, and support metabolism.
It shows how balanced your stress (fight-or-flight) and recovery systems are.
Reflects persistent immune signaling in your body that inflames tissues and speeds aging.
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When the 24 drivers come together, they tell a deeper story, one of connection, cause, and potential. They reveal how your six core dimensions work in sync to shape your HealthSpan and highlight five emerging trends that may influence your future.
For the first time, you can see not just where you are, but where you’re going.
And once you see it, everything changes.
The gradual decline in cellular repair, DNA integrity, and regenerative capacity, the foundation of aging at its core.
The stiffening of vessels and decline in cardiac function that silently raises the risk of heart disease, stroke, and reduced vitality.
The progressive loss of muscle mass, strength, and bone density that undermines mobility, stability, and independence.
The slowing of metabolic efficiency, glucose regulation, and energy production that accelerates biological aging and disease risk.
The body’s declining ability to adapt to physical, emotional, and environmental stressors, and inflammation that erodes tissues.
Chronic diseases send signals early. Not paying attention and not addressing them early causes early aging and decreased HealthSpan.
We asked a simple question: what truly defines aging and prevention? By dissecting thousands of studies, our scientists isolated the biomarkers shown to influence longevity, prevention health, and resilience. Each was chosen not just for what it measures, but for how it connects, forming a biological language that reveals why some bodies age slower than others.
Then came connection. The Empathy Engine® maps trillions of correlations across diverse global cohorts, linking biomarkers to genetics and outcomes. It finds patterns hidden from human eyes - how stress alters metabolism, how inflammation accelerates aging and more. The result: a living network of longevity that shows not just what’s happening, but what’s next.
Global data.
Multi model network.
Science alone doesn’t change lives, understanding does. 101+ gives you three powerful ways to act, bridging precision with proactive care.
Bring your personalized RCA Report, the first of its kind, to your physician. Turn your every visit into a precision partnership focused on extending your HealthSpan.
Instead of reacting to symptoms, your doctor can now see the full biological story behind your health: how your systems are aging, where stress points are forming, and and where proactive care can make the greatest impact.
Access the world’s leading longevity doctors and researchers through your 101+ membership. They’ll interpret your RCA, design targeted interventions, and suggest paths that can slow aging at its source.
This isn’t one-size-fits-all wellness. It’s scientifically tailored longevity, built for your biology, your data, your future.
Your 101.plus app becomes your living advisor, turning complex science into small, meaningful habits. Regularly, you’ll receive precise insights on what to eat and how to move, all tuned to your current 6 dimensions and RCA profile.
Each nudge is subtle, yet powerful, micro-adjustments that create macro change. Because longevity isn’t a single breakthrough, it’s a continuous rhythm of renewal for you.
Let's do it together.
101 Plus (“we,” “us,” or “our”) operates as a technology-driven longevity and wellness platform. The information, reports, and services provided on https://www.101.plus (the “Site”) and through our mobile application are for informational and educational purposes only. 101 Plus is not a medical provider and does not offer medical advice, diagnosis, or treatment. The insights, recommendations, and coaching available through the platform are designed to help users understand and support their overall wellness and longevity not to diagnose, treat, cure, or prevent any disease or medical condition. All laboratory testing and sample analysis are performed by independent, CLIA-certified laboratory partners for wellness purposes only. These tests are not intended for clinical diagnosis or to replace professional medical evaluation.The 101 Plus platform uses advanced technology, including AI-driven analytics and data visualization, to translate biological data into personalized longevity insights. These tools are not FDA-approved medical devices. All insights and guidance should be interpreted in consultation with a qualified healthcare provider for any medical concerns. By using 101 Plus, you acknowledge that you understand and agree that 101 Plus is a technology platform and not a healthcare provider. Your participation and reliance on the information provided are voluntary and at your own discretion. Always seek the advice of your physician or qualified healthcare professional before making any decisions related to your health, medications, or medical treatment.
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